Correction: DC-SIGN on B Lymphocytes Is Required for Transmission of HIV-1 to T Lymphocytes

RETINOBLASTOMA is a rare tumour, occurring mainly in infancy and early childhood, and arouses interest whenever it is encountered. This case is of even greater interest because it was found in a girl 81 years old, and even more so because of the unique method in which the diagnosis was established. Retinoblastoma, in the advanced stages, when extra-ocular extension has occurred, may present with swelling of the facial bones and exophthalmos. This may lead to difficulties in differential diagnosis between retinoblastoma and other conditions presenting with similar features in Tropical Africa. The commonest cause of swelling of facial bones and exophthalmos in the local children is, undoubtedly, malignant lymphoma (Burkitt's tumour). Other conditions, which have been observed to present with these features, include neuroblastoma, chloroma due to myeloblastic leukaemia, adamantinoma, epulis, and inflammatory conditions such as mucocele and cancrum oris. The diagnosis in most of these conditions can be established with certainly only by histological examination of a biopsy specimen. This rather cumbersome procedure was avoided by the identification and subsequent tissue culture of the retinoblastoma cells in a sample of cerebrospinal fluid taken from a lumbar puncture. What was even more important was that the result was available within half an hour of performing the lumbar puncture.